Genetics of pain and management of chronic pain by extracorporeal depuration therapies

Authors: Enrique Daniel Austin-Ward


About this article

The article delves into the intricate nature of pain, a vital biological phenomenon closely linked to the origins of consciousness and evolution. Pain, a defense mechanism against harmful stimuli, poses ethical, philosophical, religious, and scientific dilemmas. Medically, it is a primary reason for seeking healthcare, with chronic pain affecting a significant portion of the population, costing the U.S. economy billions annually. Notably, pain experiences vary widely among individuals, even with similar pathologies, rendering it a deeply subjective and complex phenomenon.

It also explores the genetic and molecular factors underlying pain, essential for understanding its mechanisms and developing more effective therapies. The study of pain involves multifaceted methodologies, aiming to decipher the biological aspects amenable to intervention or quantification in individual pain experiences.

At the end for the publication, it highlighting the intersection of genetics and pain management, the article suggests a promising avenue for intervention: Extracorporeal Circulation Devices (ECD). By addressing pain from a genetic perspective and considering innovative technologies like ECD, there is potential for groundbreaking advancements in chronic pain management. This holistic approach, encompassing genetic insights and cutting-edge interventions, underscores the ongoing efforts to alleviate the burden of pain on individuals and societies, offering hope for more tailored and effective pain therapies in the future.